Endocrine Abstracts

Introduction: Psoriasis is not only a skin disease, is a chronic inflammatory disease associated with serious comorbidities: psoriatic arthritis, metabolic syndrome (obesity, dyslipidemia and insulin resistance), Crohn’s disease, depression, ocular problems, cardio-vascular diseases (myocardial infarction), cancer.Methods: 1236 patients (male 54.13% and female 45.87%) with psoriasis were seen in an Outpatient Clinic over a period of 8 years (2004&#1...

: Sebaceous glands are very sensitive to androgens which can modify the size but not the number of sebaceous glands. Sebaceous hyperplasia is a common benign proliferation of the sebaceous glands seen during the first weeks of life, being reported in 89.4% of 1000 newborns enrolled in across-sectional prospective study in the period of November 2007 to May 2009 in India [1] or in 35% of 2938 neonates aged up to three days of life hospitalized in a Brazilian city [2]. Sebum sec...

Aim: The aim of the study was to evaluate the relation of vitiligo with thyroid autoimmunity.Materials and methods: A cross sectional study was done on 75 patients clinically diagnosed (old and new) with different types of vitiligo. Patients with known thyroid disease were excluded from the study. Serum TSH and anti-TPO antibodies were measured in all patients.Results: The prevalence of anti-TPO antibody positivity was found in 23 ...

A broad spectrum of cutaneous disorders may be diagnosed in patients with type 1 and type 2 diabetes mellitus. Some of dermatologic lesions may precede any clinical or biochemical evidence for diabetes, while others are considered well known complications of the metabolic disorder. We highlight typical, rare dermatological manifestations of diabetes, excluding infectious, disorders related to complications of diabetes mellitus and skin conditions induced by treatment of diabet...

Ganuloma annulare (GA) is a self-limited inflammatory dermatosis, clinically characterized by the presence of papules arranged in annular or circinate pattern, mostly on the extremities. GA has rarely been reported in childhood, although is a not a rare condition seen in adulthood. Aetiology and pathogenesis of GA are still unknown, although variable associations have been reported, during last decades, with diabetes mellitus, thyroid disorders, HIV infection, malignancies, tu...

Erosio interdigitalis blastomycetica is a special form candidiasis commonly seen in the third web space of digits, but can spread to all web spaces. Diagnosis is clinically suspected in the presence of maceration and ulceration, erythema, sometimes associated with pain. The main predisposing condition is chronic maceration (for example in launderers), irritant chronic agents and prolonged moisture affect skin barrier with subsequent colonization of Candida spp. Direct...

Guidelines recommend hormonal treatment in severe acne, in forms of acne with no response to standard therapeutical options, in women with proved hyperandrogenism. Hormonal therapy for acne includes oral contraceptives; anti-androgens, such as cyproterone acetate, spironolactone and flutamide; low-dose glucocorticoids and gonadotropin-releasing hormone agonists.In daily practice there are many cases with moderate to severe forms of acne, in young women w...

Case report: A 52-year-old woman had an appointment at the dermatology department for a previous diagnosis of melasma. She was seen in October and her pigmentation had appeared somewhere during summer. She did not recall any drug intake, she denied sun exposure in the recent past, and she was a social employee working indoor.At the clinical examination intense hyperpigmentation around the eyes was noted. In contrast with the rest of the skin of normal as...

Vitiligo is a common skin depigmenting disease, which is thought to have, at least partly, an autoimmune etiology.Our objective was to compare the frequency of thyroid peroxidase antibody (anti-TPO) in vitiligo patients over a period of 3 years (2010–2012) in our Department.Methods: Anti-TPO levels were assessed in order to detect any correlation with the onset, the evolution and the treatment of vitiligo. Patients with vitili...

Purpose: The purpose is to draw attention to rare cases of Pituitary Macroadenoma co-secreting Growth Hormone and Thyroid Stimulating Hormone with Polynodular Goiter and their importance and approach in current practice.Background: Pituitary adenomas with no hormonal clinical picture are known as ‘silent’ tumors. They are rarely reported and lacking pathogenic explanations.Method: We describe a case of Pituitary Macroaden...